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Our guide to every Week 4 game: Matchup previews, predictions, picks
Confirmed
In Short: ESPN's preview of the Week 4 games includes bold predictions and fantasy insights for each matchup.

The NFL's Week 4 slate is set to feature a range of matchups, with the highlight being the Monday Night Football clash between the Atlanta Falcons and New Orleans Saints.
For the Indianapolis Colts versus Washington Commanders game, defensive coordinator Daronte Jones highlighted the game-breaking speed of Taylor, while Daron Payne emphasized the importance of a physical and dominant defensive line.
In the matchup between the Jacksonville Jaguars and Cincinnati Bengals, all eyes will be on the duel between Cincinnati cornerback Dax Hill and Jacksonville wide receiver Parker Washington.
The Week 4 games also include intra-division showdowns, such as the Chiefs versus Raiders game and an NFC South matchup between the Falcons and Saints.
ESPN's Seth Walder, Ben Solak, and Eric Moody provide game projections, bold predictions, and fantasy insights for each contest.
The NFL's first regular-season game in Australia last week set the stage for the upcoming Week 4 matchup between the Los Angeles Rams and San Francisco 49ers.
Fantasy football enthusiasts are advised to capitalize on Week 4 matchups, with experts sharing insights on key players and potential performances.
The 2026 Major League Baseball Postseason is set to begin with four wild card matchups, providing a preview of the upcoming playoff action.
The WNBA playoffs are also underway, with the first-round matchups set, including a series between the New York Liberty and Minnesota Lynx.
Fans can tune in to various networks for coverage, with ABC and NBCSN providing live streams and broadcasts for the NFL and MLB games, respectively.
Background
Rams tight end Terrance Ferguson will likely miss Sunday's game against the Eagles due to a medial ankle sprain.
What's confirmed
- The NFL's Week 4 slate is set to feature a range of matchups, with the highlight being the Monday Night Football clash between the Atlanta Falcons and New Orleans Saints.
- For the Indianapolis Colts versus Washington Commanders game, defensive coordinator Daronte Jones highlighted the game-breaking speed of Taylor, while Daron Payne emphasized the importance of a physical and dominant defensive line.
- In the matchup between the Jacksonville Jaguars and Cincinnati Bengals, all eyes will be on the duel between Cincinnati cornerback Dax Hill and Jacksonville wide receiver Parker Washington.
- The Week 4 games also include intra-division showdowns, such as the Chiefs versus Raiders game and an NFC South matchup between the Falcons and Saints.
- ESPN's Seth Walder, Ben Solak, and Eric Moody provide game projections, bold predictions, and fantasy insights for each contest.
- The NFL's first regular-season game in Australia last week set the stage for the upcoming Week 4 matchup between the Los Angeles Rams and San Francisco 49ers.
- Fantasy football enthusiasts are advised to capitalize on Week 4 matchups, with experts sharing insights on key players and potential performances.
- The 2026 Major League Baseball Postseason is set to begin with four wild card matchups, providing a preview of the upcoming playoff action.
- The WNBA playoffs are also underway, with the first-round matchups set, including a series between the New York Liberty and Minnesota Lynx.
- Fans can tune in to various networks for coverage, with ABC and NBCSN providing live streams and broadcasts for the NFL and MLB games, respectively.
What's still developing
- Let's get into the full Week 4 slate, which culminates with a "Monday Night Football" matchup between the Falcons and Saints on ESPN. (Game times are Sunday unless otherwise noted, and all odds are via DraftKings.) Jump to a matchup: IND-WSH | JAX-CIN | DAL-HOU NE-BUF | LAR-PHI | NYJ-CHI TEN-BAL | GB-TB | ARI-NYG MIA-MIN | DEN-SF | LAC-SEA KC-LV | DET-CAR | ATL-NO 9:30 a.m.
- DT Daron Payne said it's just about "being real physical and dominating the line." -- John Keim Stat to know: The Colts' defense is giving up 417.3 total yards per game -- the most in the NFL. -- ESPN Research Bold prediction: Commanders WR Stefon Diggs will record at least 85 receiving yards.
- He has posted a solid 1.8 yards per route run this season, but the fact that he is being targeted on 33% of his routes suggests his production could be even stronger going forward. -- Walder Why you should watch this game: You don't need a reason to watch the London game -- it's the only game on at that time, and a great appetizer while you're toasting your bagels and brewing your coffee. -- Solak Fantasy nugget: Commanders QB Marcus Mariota finished with 20.4 fantasy points against a stout Seahawks defense in Week 3 and now faces a Colts defense that has allowed the fifth-most fantasy points to QBs.
- Lawrence said he didn't know he was winless in the series: "You don't really think about that," he said. -- Michael DiRocco What we're hearing on the Bengals: All eyes will be on the matchup between Cincinnati CB Dax Hill and Jacksonville WR Parker Washington.
- We also have Football Power Index (FPI) game projections, and Maldonado, Moody and Walder all give us final score picks for every game.
- 🎙 UPCOMING BROADCASTS - SUNDAY: 11:45 AM ET, PATRIOTS PREGAME SHOW; AFTER GAME, POSTGAME SHOW & PRESS CONFERENCE COVERAGE Forged in Foxborough Episode 3: Earn Your Role Experts share their picks for the Patriots' Week 2 matchup against the Pittsburgh Steelers.
- Here are the four series that begin Sunday, Sept. 27: At the time of publication, the WNBA has yet to assign television slots for the Game 1s.
- Not only did the lower-seeded Liberty win the season series 2-1, with the most recent win coming approximately one week ago, but some might even suggest that the Lynx “strategically” attempted to avoid this matchup, whereas the Liberty were aiming for it.
- The champs enter the series soaring, winners of seven-straight games, whereas the Fever are skidding, having been walloped by a close-to-full-strength Lynx after appearing to fly high following their own big win over Minnesota’s reserves.
- ET on ABC, with another Game 1 immediately following on ABC at 4 p.m.
- There will be a primetime Game 1 on Prime, with the final Game 1 shown on USA Network at 9 p.m.
- The biggest matchup of the weekend takes place right out of the gate on Saturday afternoon, with Arch Manning and the No.
