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McCaffrey Returns After Thigh Injury in 49ers Win

Confirmed

Sports Desk

In Short: San Francisco 49ers running back Christian McCaffrey returned to the game after suffering a thigh injury against the Atlanta Falcons.

Christian McCaffrey Injury Update: 49ers RB Heads to Locker Room vs Falcons
YouTube — American Sports Zone

San Francisco 49ers running back Christian McCaffrey returned to the game after suffering a thigh injury during the first half against the Atlanta Falcons on Sunday.

McCaffrey was hurt after scoring a 1-yard touchdown, giving the 49ers an early lead.

YouTube — American Sports Zone YouTube

He was checked out in the injury tent and then came back out to do some running on the sideline with his helmet on.

McCaffrey returned to the field for San Francisco’s first possession of the third quarter.

In six games this year, McCaffrey has rushed for 350 yards and seven touchdowns while averaging 4.5 yards per carry.

McCaffrey was voted as the No. 6 player in the NFL's 'Top 100 Players of 2026' list, highlighting his importance to the team.

The 49ers have named McCaffrey as one of their eight team captains for the 2026 NFL season.

McCaffrey's injury history includes a PCL sprain in 2024, a pedal Achilles sprain in the same year, a left calf strain in 2023, and a thigh hamstring strain in 2021.

The San Francisco 49ers look like the best team in football to start the 2026 season, and keeping McCaffrey healthy and productive has been a big reason why.

The other top-earning running backs in the NFL include Saquon Barkley of the Eagles at $20.6 million per year, Christian McCaffrey of the 49ers at $19 million per year, Devon Achane of the Dolphins at $16 million per year, and Derrick Henry of the Ravens at $15 million per year.

Backup running back Kaelon Black picked up where McCaffrey left off by ripping a 30-yard touchdown run as McCaffrey was getting looked at on the bench.

What this adds

The team has also made clear through its injury reporting that there is no current designation keeping McCaffrey from playing.

What's confirmed

What's still developing

Sources