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Week 7 College Football: Top Matchups and Betting Predictions

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Sports Desk

In Short: Week 7 of the college football season features high-profile matchups and lucrative betting opportunities.

College Football Picks Today 10/15/26 CFB NCAAF Week 7 Picks & Predictions
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Week 7 of the college football season promises to be a thrilling weekend with six matchups featuring Top 25 teams, including the afternoon clash between Ohio State and Indiana and the prime-time showdown between Notre Dame and BYU.

College football fans can look forward to blockbuster matchups during each timeslot, ensuring that viewers will be glued to their televisions throughout the day.

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The Michigan Wolverines, fresh off a controversial win over Western Michigan, face a tough challenge at home when they host the Oklahoma Sooners in a marquee showdown.

Houston ranks 28th in the FBS with a 71.4 red-zone touchdown rate, while OSU ranks 117th at 51.7 percent, highlighting the offensive struggles OSU has faced.

Tennessee gave Texas a scare a few weeks ago, limiting the Longhorns to just 262 yards despite losing 20-17. However, the problem is the offense mustered only 221 yards while yielding 12 tackles for loss.

The betting odds for the East Carolina Pirates vs. UAB Blazers in Week 7 have been released, with documented handicapping data tracked by CappersPicks since 2004.

Fantasy football enthusiasts should capitalize on the Week 4 matchups, with a focus on the best Penn State game.

ESPN College GameDay is setting up shop on campus ahead of the big game, which will be attended by President Donald Trump, so all eyes will be on the Vols leading up to kickoff.

The full Week 4 TV schedule for the 2026 college football season can be seen below, with all times Eastern.

Ole Miss was 11-1 last season and clinched a spot in the College Football Playoff for the first time, but Kiffin left the program before the playoff even began to take over the LSU job in what ended up as a very messy divorce.

Chambliss has been especially potent under pressure, posting a higher PFF grade there than when he’s kept clean (84.6 to 84.2).

The betting odds for the National Championship in the 2026 college football season have been updated after Week 6, with the latest odds reflecting the current standings.

What this adds

Week 7 of the college football season features a mix of historic rivalries and marquee matchups, providing ample opportunities for betting and fantasy football enthusiasts.

The Week 4 TV schedule includes a Thursday night matchup between the Cowboys and another team, setting the stage for an early weekend of football.

The LSU-Ole Miss matchup is a highly anticipated return for Lane Kiffin to Oxford, adding another layer of drama to the College Football Playoff race.

The betting odds for the National Championship are closely watched by fans and analysts, with the latest updates reflecting the current form and potential of each team.

Background

Week 6 of the college football season features high-profile matchups and lucrative betting opportunities.

Week 6 of the college football season features high-profile matchups and lucrative betting opportunities.

What's confirmed

What's still developing

Sources