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Florida Sees Spike in Dengue Cases, Signals Wider Threat
Developing
In Short: Despite the growing threat, there is currently no dengue vaccine available in the United States.
Florida is witnessing a significant increase in locally acquired dengue cases, with 252 reported cases as of the 38th week of 2025, compared to 40 cases and 37 cases in the same period in 2024 and 2023, respectively.
The surge in dengue cases in Florida is part of a broader global trend. In 2024, the world saw a historic outbreak with over 14.6 million cases reported, leading to more than 10 million cases and over 6000 deaths.
Experts are concerned about the potential for dengue to spread further. Dr. Small, a researcher, noted, “This virus just kind of comes out of nowhere.” She emphasized the need for awareness, stating, “She met the wrong mosquito, and that’s it.”
The increase in local transmission is particularly alarming given the historical pattern of travel-acquired dengue cases. In 2024, Florida saw 245 travel-related cases, a stark contrast to the current trend where local transmission is on the rise.
Florida’s close ties to the Caribbean and South America, regions where dengue is more prevalent, have long contributed to the state’s dengue cases. However, the recent surge in local transmission suggests a shift in the pattern.
Researchers liken subsequent dengue infections to a Trojan horse, explaining why they tend to be more severe than initial infections. Dr. Miley, a researcher, said, “You’re actually opening the door and letting it invade.”
Dr. Miley also highlighted the potential benefits of a vaccine for regions like Brazil, where a large proportion of the population may have already been infected with at least one type of dengue.
Despite the growing threat, there is currently no dengue vaccine available in the United States. Takeda’s Qdenga vaccine application was withdrawn in 2023 due to disagreements over data collection.
In an effort to raise awareness, Small spoke to the media about her mother’s fatal dengue case. She said, “If she can let people know the severity of this, maybe it will give her death meaning.”
Experts warn that the current surge in Florida could be indicative of a longer-term trend, with dengue potentially becoming more widespread globally.
What's still developing
- The European Union’s pharmaceutical regulator cleared it in 2022.
- The equivalent number for this year is 245 travel-related cases.
- There are several reasons for this, including dengue’s historic relatively low prevalence nationwide.