Home · Health · Oct 5 archive
UTI Drug Improves Symptoms Within a Day
Confirmed
In Short: A study published in JAMA Network Open shows that more than half of women treated with gepotidacin for uncomplicated urinary tract infections experienced symptom improvement within 24 hours.
A study published in JAMA Network Open this week found that more than half of women treated with gepotidacin for uncomplicated urinary tract infections (UTIs) experienced symptom improvement within 24 hours of starting the antibiotic.
Researchers enrolled 97 girls and women with at least two symptoms of uncomplicated UTI, including dysuria, increased urination frequency, and lower abdominal or pelvic pain.
Nearly 80% of patients' symptoms improved by 48 hours, although complete symptom resolution took a little over a week.
Gepotidacin, a first-in-class oral antibiotic approved by the FDA in 2025 for females aged 12 years and older, is designed to treat uncomplicated UTIs when caused by certain bacteria that are susceptible to the drug.
The rapid improvement in symptoms is significant, especially for patients with recurrent UTIs, who often face an increasing incidence of drug-resistant bacteria, leaving clinicians with fewer oral treatment options.
However, Dr. Siddiqui, a researcher involved in the study, cautioned against overutilizing the drug, warning that it could lead to the development of drug-resistant bacteria.
She also noted that gastrointestinal symptoms are common with antibiotics generally and should be weighed against a patient's need for treatment.
"Everyone wants to feel better faster," but because the study did not include a comparison group, "you can't take this out of context and basically say that this is going to work faster than other [antibiotics]," Siddiqui said.
The study adds to the growing body of research on the effectiveness of gepotidacin and its potential to address the challenges posed by drug-resistant bacteria in treating UTIs.
What's confirmed
- “Consuming excessive fibre can trigger a series of uncomfortable reactions within your body. When you overload your system with fibre, it struggles to keep up with processing all that bulk. This can lead to a trio of unpleasant digestive issues: bloating, gas, and diarrhoea,” she said.
- It not only prevents constipation but also improves gut health by allowing food particles to ferment and break down more effectively.
- The supermarket detected listeria monocytogenes within 120g packets of Waitrose Essential Pitted Black Olives.
- According to the Food Standards Agency, symptoms caused by listeria can resemble flu, including a high temperature, muscle aches or pain, chills, feeling or being sick and diarrhoea.
- The 500g product has a use-by date of 19 August 2026 but has home freezing instructions to consume within one month of freezing.
What's still developing
- Bagent remains in concussion protocol and will need to go consecutive days without symptoms after practice to be fully cleared.
- However, his return to practice is a key advancement within the protocol.
- Memory loss is one of the earliest symptoms of Alzheimer’s, along with a gradual decline of other intellectual and thinking abilities (called cognitive functions), and changes in personality or behavior.
- Alzheimer was a pioneer in linking the symptoms of what we now call Alzheimer’s disease to the abnormal clumps ( amyloid plaques ) and tangled bundles of fibers (neurofibrillary tangles or tau) in the brain.
- Scientific researchers have made huge strides in understanding Alzheimer’s, offering that effective treatments, and possibly even a cure, are now within reach.
- Browse this section to learn about the possible causes of Alzheimer’s disease, what happens to the brain as the disease progresses, and the risk factors and symptoms of Alzheimer’s.
- July 7th, 2026 | Housing & Health Equity New York City is once again dealing with a Legionnaires’ Disease outbreak, this time on the Upper East Side (specifically, within a one-mile radius in Carnegie Hill and Yorkville).
- Symptoms might develop anywhere between two days and two weeks of exposure.
- If you have been near the affected zip codes and develop symptoms like: Please seek immediate medical attention, especially if you’re over 50 years old, smoke, or have a chronic health condition.
- Check regularly on your family and neighbors, as such common symptoms can easily be ignored by those unaware of the outbreak.
- Single-cell RNA sequencing from human PDAC tumors revealed that immune cells within the tumor microenvironment expressed genes encoding a glycoprotein.
- A minority of pancreatic cancers also emerge within hormone-producing cells of the pancreas.