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RSV-B Bronchiolitis Linked to Worse Symptoms in Childhood
Developing
In Short: Researchers found that children and adolescents who had severe bronchiolitis caused by RSV subgroup B in their first two years of life were more likely to experience symptoms like wheezing that restricted speech and nighttime dry cough at school age.
According to the study, the prevalence of current asthma and lung function did not differ significantly between those with RSV-B and RSV-A bronchiolitis.
The study's authors suggest that closer monitoring and better medical management of respiratory symptoms in the first years of life could help reduce medium-term morbidity in this patient group.
However, the study faced limitations, including a smaller sample size than originally planned and an unequal distribution of participants between the RSV-B and RSV-A groups.
Symptoms were assessed at a single visit and relied on patient recall, which could introduce recall bias.
What's still developing
- Among children and adolescents hospitalized for severe bronchiolitis in the first 2 years of life, those whose illness was caused by respiratory syncytial virus (RSV) subgroup B were more likely than those with RSV subgroup A to report wheezing that restricted speech and nighttime dry cough at school age, whereas current asthma prevalence and lung function did not differ significantly.
- Symptoms were assessed at a single visit and relied on recall, and many eligible patients did not enroll, mostly for logistical reasons; therefore, recall and selection bias may have affected the results.
Sources
- Medscapelink