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European Ash Pangenome Aids Resistance to Ash Dieback

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In Short: A new genetic resource could help scientists identify and breed trees naturally resistant to the fungal disease.

Ash tree with ash dieback disease
Photo: Bizzarle / Wikimedia Commons (CC BY-SA 4.0)

Researchers have unveiled the first European ash (Fraxinus excelsior) pangenome, a comprehensive genetic resource that captures the full range of genes found across multiple individuals of the species.

This pangenome, constructed from DNA of 50 diverse trees, has identified 211 genes with possible links to ash dieback resistance, including 16 dispensable genes present in some but not all trees.

According to the Forestryjournal, a traditional genome assembly approach only captures information from a single individual, whereas a pangenome allows for the identification of dispensable genes that may confer advantageous traits like disease resistance.

Last year, researchers from Kew and Queen Mary University of London discovered that a young population of ash trees in East Surrey were evolving resistance to ash dieback, demonstrating natural selection in action.

Unlocking these data could enable researchers to predict which trees are genetically shielded against ash dieback and help breed resistant populations by identifying the most promising trees from their genetic code alone.

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