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NFL Week 1 Games Preview: Rams vs 49ers in Australia

Confirmed

Sports Desk

In Short: The NFL's first-ever game in Australia between the 49ers and Rams highlights Week 1, with predictions and picks from experts.

SportsLine's team of NFL experts have analyzed the 49ers vs. Rams matchup, the first-ever NFL game in Australia, and revealed their two best bets for the game. The NFC West rivals split their season series last year, with the road team winning both matchups. Matthew Stafford had seven touchdowns and zero interceptions in those games, while the 49ers were without key players Brock Purdy and Nick Bosa. The game will be a key division rivalry and a significant test for both teams as they start the 2026 season.

Cohen, a SportsLine expert and host, is evaluating the entire Week 1 NFL slate and delivering score predictions and logic for each matchup. He notes that Josh Allen, the quarterback for the Bills, has struggled in away games, with 10 turnovers in three starts compared to just five passing touchdowns. Bettors can also make exact score predictions, which could be helpful given the unexpected outcomes in the first two games of the season.

The NFL's decision to host this game in Australia has faced criticism, with Fox News pointing out the inclusion of a speech by Aunty Joy Murphy Wandin during the pregame ceremony, which some found off-putting. The speech, set in 60,000 years ago, has raised questions about the appropriateness of the narrative in a 9/11 pregame memorial. Despite the controversy, the game is a significant event for both teams and for the league's international expansion.

CappersPicks offers a free NFL football pick based on matchup analysis and documented handicapping data for the 49ers vs. Rams game. The article also highlights the best player matchups to watch, including the head-to-head battles between key players like Garrett and Williams. PFF notes that this matchup could carry season-long weight between two teams competing for the NFC West crown, with Smith-Njigba's performance in Super Bowl 60 being a key factor.

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