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49ers vs. Rams Kickoff in Australia: Key Matchup Details
Confirmed
In Short: The San Francisco 49ers and Los Angeles Rams will face off in the first-ever NFL Melbourne Game on Thursday, September 7.
San Francisco 49ers and Los Angeles Rams will kick off their 2026 seasons in the first-ever NFL Melbourne Game on Thursday, September 7, at Melbourne Cricket Ground. The game, which marks a significant milestone for the NFL in expanding its international footprint, will be a crucial matchup for both teams, especially given their recent performances.
Despite the 49ers' divisional round loss to the Seahawks and the Rams' narrow victory over the Seahawks in the NFC Championship, the Rams will be without key player Aaron Donald, who was ruled out earlier this week. However, defensive player Nacua is expected to handle his usual role, making his health a critical factor for the Rams.
Experts predict a close game, with Rams picks ranging from 24-17 to 31-21 over the 49ers. While the Rams are favored to win Super Bowl LXI at +500, the 49ers' travel fatigue and the 17-hour time difference could be significant factors. The game, scheduled for 10:35 a.m. local time, will be a unique experience for both teams and fans.
What's confirmed
- The San Francisco 49ers and Los Angeles Rams meet Thursday, Sept.
- Seattle routed the 49ers 41-6 in the divisional round, then beat the Rams 31-27 in the NFC Championship Game, one win short of Super Bowl LX.
- He was not listed on the Rams injury report released Tuesday after dealing with a core issue, and that points to him being expected to handle his usual role against San Francisco.
- With the Rams still waiting for regular season statistical leaders to emerge, Nacua stands out as a proven focal point whose health is one of the most relevant developments going into this opener.
What's still developing
- Stay connected with the 49ers by following along on each of the team's social media channels: Broadcast and streaming information for the San Francisco 49ers preseason matchup against the Las Vegas Raiders at Allegiant Stadium.
- Broadcast and streaming information for the 2026 NFL Pro Bowl Games in San Francisco.
- Broadcast and streaming information for the San Francisco 49ers Wild Card matchup against the Philadelphia Eagles at Lincoln Financial Field.
- Broadcast and streaming information for the San Francisco 49ers Week 17 matchup against the Chicago Bears at Levi's® Stadium.
- Rams SGP could go in a number of different directions.
- Rams in the NFL Australia Game 2026 and locked in confident rated prop bets for an NFL SGP you can lock in at betting sites.
- Visit our DraftKings promo code review and get $200 in bonus bets as a new user after $5+ in wagers here : After simulating Rams vs.
- If you're thinking about betting on the game, here are a couple of props I like: Finally, if you're wondering who we're picking, here's who we have: My pick: Rams 24-17 over 49ers Pete Prisco's pick: Rams 28-27 over 49ers Jared Dubin's pick: Rams 31-21 over 49ers Jordan Dajani's pick: Rams 24-20 over 49ers Tyler Sullivan: 49ers 27-24 over Rams Over on our CBS Sports picks page, we have seven experts, and five of us are taking the Rams to win straight-up, but only four of us have them covering.