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Our Fat Tissue May 'Remember' Obesity, Even After We've Lost Weight

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Now a new study published in Science Translational Medicine describes a separate impact that obesity has on a different set of immune cells, located right inside fat tissue – and apparently leading to permanent biological changes that directly interfere with fat loss.

During experiments on mice bred to gain and then lose weight , the study team found permanent changes in the ATM cells of the animals relating to mRNA splicing, the editing process that controls how genetic instructions are compiled to make proteins.

A study published earlier this year showed one way that our immune cells carry 'memories' of obesity around with them.

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